Samuel Refetoff Selected Research

Allan-Herndon-Dudley syndrome

1/2022	AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.
1/2021	Measurement of Reverse Triiodothyronine Level and the Triiodothyronine to Reverse Triiodothyronine Ratio in Dried Blood Spot Samples at Birth May Facilitate Early Detection of Monocarboxylate Transporter 8 Deficiency.
10/2014	Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
7/2013	Changes in thyroid status during perinatal development of MCT8-deficient male mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Samuel Refetoff Research Topics

Disease

25	Congenital Hypothyroidism (Cretinism) 12/2022 - 10/2003
23	Hypothyroidism 01/2022 - 04/2002
10	Goiter 01/2022 - 01/2004
6	Thyroid Neoplasms (Thyroid Cancer) 01/2021 - 07/2003
6	Neoplasms (Cancer) 01/2021 - 01/2011
6	Hyperthyroidism 01/2020 - 12/2004
6	Thyroid Diseases (Thyroid Disease) 01/2017 - 12/2003
4	Allan-Herndon-Dudley syndrome 01/2022 - 07/2013
4	Carcinogenesis 11/2021 - 01/2011
4	Familial Dysalbuminemic Hyperthyroxinemia 01/2020 - 06/2014
4	Carcinoma (Carcinomatosis) 10/2019 - 01/2011
4	Graves Disease (Basedow Disease) 05/2008 - 12/2003
3	Papillary Thyroid Cancer 01/2021 - 12/2011
3	Disease Progression 01/2021 - 05/2009
3	Thyroid Dysgenesis (Thyroid Agenesis) 07/2013 - 07/2005
3	Hypoxia (Hypoxemia) 01/2006 - 02/2005
2	Abnormal Thyroid Hormone Metabolism 10/2021 - 01/2021
2	Non-alcoholic Fatty Liver Disease 01/2021 - 01/2019
2	Neurodevelopmental Disorders 01/2021 - 05/2009
2	Hashimoto Disease (Thyroiditis, Hashimoto) 12/2019 - 12/2004
2	Osteoporosis 01/2017 - 02/2008
2	Body Weight (Weight, Body) 01/2017 - 04/2016
2	Inflammation (Inflammations) 10/2016 - 03/2002
2	Intellectual Disability (Idiocy) 11/2015 - 06/2013
2	Nonautoimmune Hyperthyroidism 01/2014 - 04/2006
2	Thyrotoxicosis 12/2013 - 08/2004
2	Adenoma (Adenomas) 06/2013 - 02/2009
2	Inherited Thyroxine-Binding Globulin Deficiency 12/2003 - 03/2002
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Hyperplasia 01/2021
1	Thyroid Nodule (Nodule, Thyroid) 01/2021
1	Anaplastic Thyroid Carcinoma 10/2019
1	Glycogen Storage Disease Type I 01/2019
1	Hepatorenal form of glycogen storage disease 01/2019
1	Deafness (Deaf Mutism) 10/2018
1	Pituitary Neoplasms (Pituitary Adenoma) 12/2016
1	Hearing Loss (Hearing Impairment) 06/2013
1	Respiratory Tract Infections (Respiratory Tract Infection) 06/2013
1	Seizures (Absence Seizure) 12/2012
1	Lung Injury 12/2011
1	Acute Lung Injury 12/2011
1	Hypersensitivity (Allergy) 04/2011

Drug/Important Bio-Agent (IBA)

28	Thyroid HormonesIBA 12/2022 - 01/2004
12	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2022 - 07/2003
8	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2022 - 01/2004
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2003
7	Thyroxine (Levothyroxine)FDA LinkGeneric 11/2021 - 08/2003
7	Iodide Peroxidase (Deiodinase)IBA 10/2021 - 05/2007
7	Dual OxidasesIBA 01/2019 - 07/2006
6	IodidesIBA 01/2022 - 10/2003
6	Thyroglobulin FDA Link 01/2022 - 05/2005
6	Thyrotropin Receptors (Thyrotropin Receptor)IBA 01/2014 - 11/2003
5	Transcription Factors (Transcription Factor)IBA 01/2021 - 12/2005
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 04/2004
3	Thyroid Hormone Receptors beta (TR beta)IBA 01/2022 - 08/2002
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2014 - 01/2011
3	PhosphofructokinasesIBA 01/2006 - 02/2005
3	Hormones (Hormone)IBA 12/2003 - 03/2002
2	prolinedithiocarbamate (PDTC)IBA 10/2019 - 10/2014
2	Doxycycline (Periostat)FDA LinkGeneric 01/2018 - 12/2011
2	CytokinesIBA 10/2016 - 12/2011
2	Oncogene Proteins (Oncogene Protein)IBA 12/2011 - 01/2011
2	Messenger RNA (mRNA)IBA 04/2009 - 04/2002
2	AntibodiesIBA 02/2008 - 05/2003
2	Glucose (Dextrose)FDA LinkGeneric 01/2006 - 12/2005
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2006 - 12/2005
2	AutoantibodiesIBA 12/2004 - 05/2003
2	beta Subunit Thyrotropin (Thyrotropin-beta)IBA 08/2004 - 04/2002
2	Thyroxine-Binding GlobulinIBA 12/2003 - 03/2002
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022
1	transgelinIBA 01/2022
1	AntioxidantsIBA 01/2021
1	Colloids (Colloid)IBA 01/2021
1	ChromatinIBA 01/2021
1	LipidsIBA 01/2021
1	Reverse TriiodothyronineIBA 01/2021
1	Phenobarbital (Luminal)FDA Link 01/2020
1	Anaplastic Lymphoma KinaseIBA 10/2019
1	Cysteine (L-Cysteine)FDA Link 01/2019
1	2- ((3,5- dimethyl- 4- (4'- hydroxy- 3'- isopropylbenzyl)phenoxy)methyl)- 4- (3- chlorophenyl)- 2- oxido(1,3,2)dioxaphosphonaneIBA 01/2019
1	GlycogenIBA 01/2019
1	ChloridesIBA 10/2018
1	AnionsIBA 10/2018
1	Human Serum Albumin FDA LinkGeneric 01/2018
1	Thyrotropin-Releasing Hormone Receptors (Thyrotropin Releasing Hormone Receptor)IBA 01/2017
1	acylcarnitineIBA 01/2017
1	Immunoglobulins (Immunoglobulin)IBA 01/2017
1	Interleukin-4 (Interleukin 4)IBA 10/2016
1	RNA (Ribonucleic Acid)IBA 10/2016
1	obatoclaxIBA 10/2014
1	AlbuminsIBA 06/2014
1	Codon (Codons)IBA 12/2013
1	Biomarkers (Surrogate Marker)IBA 12/2013
1	ChemokinesIBA 12/2011
1	IodineIBA 08/2011
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 04/2011

Therapy/Procedure

6	Therapeutics 01/2021 - 10/2003
2	Injections 01/2017 - 04/2016
1	Enteral Nutrition (Feeding, Tube) 12/2012
1	Drug Therapy (Chemotherapy) 12/2011